Effects of Total Intravenous Anesthesia and Inhalational Anesthesia on Postoperative Recovery in Patients Undergoing Transsphenoidal Pituitary Surgery:A Systematic Review.
10.3881/j.issn.1000-503X.16159
- Author:
Yun-Ying FENG
1
;
Yu-Pei ZHANG
2
;
Yue-Lun ZHANG
3
;
Bing XING
4
;
Wei LIAN
4
;
Xiao-Peng GUO
4
;
Lu-Lu MA
1
;
Yu-Guang HUANG
1
Author Information
1. Department of Anesthesiology, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
2. Department of Pulmonary and Critical Care Medicine, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
3. Center for Prevention and Early Intervention,National Infrastructures for Translational Medicine,Institute of Clinical Medicine, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
4. Department of Neurosurgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Systematic Review
- Keywords:
inhalational anesthesia;
pituitary tumor;
postoperative recovery;
total intravenous anesthesia
- MeSH:
Humans;
Anesthesia, Intravenous;
Pituitary Neoplasms/surgery*;
Anesthesia, Inhalation;
Randomized Controlled Trials as Topic;
Anesthesia Recovery Period;
Pituitary Gland/surgery*;
Postoperative Period
- From:
Acta Academiae Medicinae Sinicae
2025;47(3):434-440
- CountryChina
- Language:English
-
Abstract:
Objective To systematically evaluate the effects of total intravenous anesthesia and inhalational anesthesia on postoperative recovery in patients undergoing transsphenoidal pituitary tumor resection.Methods A comprehensive search was conducted in international biomedical databases including Ovid Medline,Embase,CINAHL(EBSCO),Cochrane Library,and Web of Science,from inception to July 4,2023.Additionally,ClinicalTrials.gov and the World Health Organization International Clinical Trials Registry Platform were searched for ongoing and completed trials.The randomized controlled trials(RCT)comparing total intravenous anesthesia and inhalational anesthesia in patients undergoing transsphenoidal surgery for pituitary tumors were included.The methodological quality of the included studies was evaluated by the Cochrane Collaboration tool.Relevant data were extracted and synthesized for analysis.Results A total of 327 records were identified,of which eight RCTs met the inclusion criteria.Four studies showed that the patients receiving desflurane or sevoflurane anesthesia experienced faster emergence from anesthesia than those receiving propofol.Two studies indicated that patients in the propofol group had lower levels of emergence agitation and a lower incidence of early postoperative nausea and vomiting.The results on postoperative cognitive function were inconsistent across studies.No differences were found between the groups in terms of postoperative complications or overall recovery quality during hospitalization.Conclusions Inhalational anesthesia appears to provide an advantage in promoting faster emergence following transsphenoidal pituitary surgery,whereas total intravenous anesthesia may contribute to smoother and more stable recovery.Further high-quality studies are needed to clarify the effects of different anesthetic techniques on both short- and long-term postoperative recovery.
