Advances in the Correlation Between White Matter Hyperintensity and Subjective Cognitive Decline.
10.3881/j.issn.1000-503X.15966
- Author:
Jing-Shi ZHANG
1
;
Guo-Yun LIU
1
;
An-Qi SHI
1
;
Ze-Qiu YANG
1
;
Yerebake MAMUKE
1
;
Jun WANG
1
;
Chao-Qun YAN
1
Author Information
1. Department of Acupuncture and Moxibustion,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China.
- Publication Type:Review
- Keywords:
Alzheimer’s disease;
subjective cognitive decline;
white matter hyperintensity
- MeSH:
Humans;
White Matter/pathology*;
Cognitive Dysfunction/pathology*;
Alzheimer Disease/pathology*;
Magnetic Resonance Imaging
- From:
Acta Academiae Medicinae Sinicae
2025;47(1):110-117
- CountryChina
- Language:English
-
Abstract:
As the population is aging rapidly,the incidence of Alzheimer's disease(AD)is increasing year by year.The World Health Organization stresses that early prevention plays a key role in reducing the incidence of AD.Subjective cognitive decline(SCD)is an early window of AD development,and timely intervention can effectively slow down the progression of the disease or prevent it from developing into dementia,thus reducing the burden on the society.White matter hyperintensity(WMH)can effectively reflect white matter changes and provide strong evidence to identify SCD.In this paper,we review the recent research progress in WMH and SCD,reveal the problems in the current research on WMH,explain the correlation between WMH and SCD in terms of physiopathology and cognitive function,and put forward several suggestions for the future research.
