Applications of ferritin nanoparticles in biological fields.

Author: Yue ZHANG ¹ ; Yi RU ¹ ; Rongzeng HAO ¹ ; Yajun LI ² ; Longhe ZHAO ¹ ; Yang YANG ¹ ; Bingzhou LU ¹ ; Huanan LIU ¹ ; Haixue ZHENG ¹
Author Information

1. State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, Gansu, China.
2. College of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, Gansu, China.
Publication Type:English Abstract
Keywords: bioimaging; ferritin; nanomedicines; nanoparticle vaccines
MeSH: Ferritins/chemistry*; Nanoparticles/chemistry*; Humans; Nanomedicine/methods*; Animals
From: Chinese Journal of Biotechnology 2025;41(7):2501-2518
CountryChina
Language:Chinese
Abstract: Ferritin, a ubiquitous protein in living organisms, plays a crucial role in storing and converting iron, as well as maintaining cellular iron metabolism balance. Due to the ability of self-assembling into unique nanocage-like structures in vitro and the special physicochemical properties, ferritin has garnered extensive attention in the biomedical field. This paper provides a brief overview of the structure and cargo loading strategies of ferritin, with a specific focus on its applications in various biological fields such as nanomedicine, bioimaging, and nanoparticle vaccine carriers. The aim is to offer a valuable reference for the future research involving ferritin nanoparticles.