Application of growth factors and their mimetics in tissue repair.

Author: Zhuanglin HUANG ¹ ; Yufeng CHEN ² ; Yuanling LIU ² ; Hong LIANG ³
Author Information

1. Department of Pharmacy, Fujian Vocational College of Bioengineering, Fuzhou 350007, Fujian, China.
2. College of Biological Science and Engineering, Fuzhou University, Fuzhou 350108, Fujian, China.
3. College of Geography and Oceanography, Minjiang University, Fuzhou 350108, Fujian, China.
Publication Type:English Abstract
Keywords: growth factor; mimetics; regenerative medicine; tissue repair
MeSH: Intercellular Signaling Peptides and Proteins/therapeutic use*; Humans; Tissue Engineering/methods*; Regenerative Medicine/methods*; Animals; Wound Healing/drug effects*; Biomimetic Materials
From: Chinese Journal of Biotechnology 2025;41(4):1291-1308
CountryChina
Language:Chinese
Abstract: Growth factors (GFs) are a class of peptides that facilitate cell growth by binding to specific receptors on the cell membrane. With unique properties, GFs are widely applied in the repair of injured tissue. To address the limitations associated with natural peptide-based GFs and recombinant GFs, researchers have developed diverse GF mimetics. This article offers a comprehensive review on common types of GFs and their applications in tissue repair and summarizes the features of GF mimetics currently under development. The aim is to provide valuable references for promoting the application of GFs in regenerative medicine.