Visualization of flagella and its applications in research on flagellar functions.

Dongyang KONG; Lu WANG; Hong ZHANG; Jingchao ZHANG

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Visualization of flagella and its applications in research on flagellar functions.

Author: Dongyang KONG ¹ ; Lu WANG ² ; Hong ZHANG ³ ; Jingchao ZHANG ⁴
Author Information

1. Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China.
2. China Petroleum Corporation Science and Technology Research Institute Co., Ltd., Beijing 100083, China.
3. Petrochemical Research Institute of PetroChina Co., Ltd., Beijing 102206, China.
4. Medical Genetics Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, China.
Publication Type:English Abstract
Keywords: flagellum; function; motility; pathogenicity; visualization
MeSH: Flagella/physiology*; Bacterial Physiological Phenomena; Chemotaxis/physiology*; Bacteria
From: Chinese Journal of Biotechnology 2025;41(1):117-130
CountryChina
Language:Chinese
Abstract: Flagella are important protein structures on the cell surface of bacteria and the main appendage for bacterial swimming. Flagella play a crucial role in bacterial motility, chemotaxis, pathogenicity, and environmental sensing. With the development of microscopic tracking technology and flagellum visualization tools, new forms of flagellar motility and increasing roles of flagella in the physiological activities of bacteria have been discovered. This review introduces the visualization methods of flagella and the applications of these methods in studying flagellar functions, giving insights into exploring the functions of flagella and laying a theoretical foundation for its future applications in inhibiting bacterial transmission and treating bacterial infections.