Research progress of antibody technology in rapid detection of foodborne pathogens.
- Author:
Meilin QUAN
1
;
Fei LI
2
;
Jinyan LIU
3
;
Tingting WANG
3
;
Rui NIAN
3
;
Wenshuai LIU
3
;
Ming ZHANG
2
;
Zhe CHI
1
Author Information
- Publication Type:English Abstract
- Keywords: antibodies; foodborne diseases; foodborne pathogens; rapid detection; specific recognition
- MeSH: Foodborne Diseases/prevention & control*; Food Microbiology; Antibodies, Monoclonal/biosynthesis*; Antibodies/immunology*; Humans; Food Contamination/analysis*
- From: Chinese Journal of Biotechnology 2024;40(11):3985-4005
- CountryChina
- Language:Chinese
- Abstract: Foodborne pathogens are one of the major factors leading to food safety issues, causing harm to the national economy and people's livelihood. Achieving rapid detection of foodborne pathogens is currently a key strategy for preventing and controlling foodborne diseases. Antibodies naturally possess high specificity and sensitivity, serving as preferred tools for specific recognition of foodborne pathogens. We list the main methods for detecting foodborne pathogens, introduce the evolution and development of polyclonal antibodies, monoclonal antibodies, and genetically engineered antibodies, and review the application of different antibody technologies in the rapid detection of foodborne pathogens. Furthermore, we recognize that the combination of antibody technology and other foodborne pathogen detection methods is currently a reliable means to improve detection performance. Finally, we elaborate on the existing limitations of different antibodies and summarize the current research status and potential issues, aiming to provide a theoretical basis and practical ideas for the development of rapid detection of foodborne pathogens.
