Meta-analysis of sealants versus fluoride varnishes for the prevention of occlusal surface caries in children's first permanent molars.
10.7518/hxkq.2025.2024418
- Author:
Jingya HAN
1
;
Yajun ZHANG
1
;
Mengzhen JI
1
;
Jingfei SUN
1
;
Shuhan JIA
2
;
Zhifeng WANG
1
Author Information
1. Dept. of Paediatric Dentistry, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan 250012, China.
2. Dept. of Stomatology, Yancheng No.1 People's Hospital, Yancheng 224000, China.
- Publication Type:English Abstract
- Keywords:
Meta-analysis;
caries prevention;
first permanent molar;
fluoride varnish;
pit and fissure sealant
- MeSH:
Humans;
Pit and Fissure Sealants/therapeutic use*;
Dental Caries/prevention & control*;
Molar;
Child;
Fluorides, Topical/therapeutic use*;
Dentition, Permanent
- From:
West China Journal of Stomatology
2025;43(3):383-394
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVES:To assess the effectiveness of the comparison between pit and fissure sealants and fluoride varnishes, as well as various types of sealants, in preventing caries on the occlusal surface of children's first permanent molars (FPM).
METHODS:Conduct a comprehensive search of literature published between January 1, 1988, and May 30, 2024, in the following databases: China National Knowledge Infrastructure, Web of Science, Cochrane Library, Embase, PubMed, China Science Periodical Database and China Biology Medicine database. Meta-analysis and subgroup analyses were performed on the literature that met the inclusion criteria.
RESULTS:A total of 5 618 pieces of literature were retrieved, resulting in the inclusion of 14 in the study. Meta-analysis showed that there was no statistically significant difference in the efficacy between varies pit and fissure sealants compared to fluoride varnishes, and between varies types of sealants in preventing caries on the occlusal surface of children's first permanent molars within 24 months post-surgery (P>0.05).
CONCLUSIONS:Within 24 months, there was no significant difference in the effectiveness of using resin-based or glass iomomer pit and fissure sealants compared with fluoride varnishes in preventing occlusal caries in FPM in children; within 24 months, there was no significant difference in the effectiveness of using resin-based sealants compared with ART sealants in preventing occlusal caries in FPM in children. ART sealants are recommended over resin-based sealers for children who have no conditions for chair-side manipulation or who are poorly co-operative.
