Relationship between fluid shear stress in alveolar bone under orthodontic forces and bone remodeling rate.
10.7518/hxkq.2025.2024288
- Author:
Bin WU
1
;
Kexin HU
1
;
Fan YANG
2
;
Yi LU
1
;
Di JIANG
1
;
Yang YI
1
;
Bin YAN
2
Author Information
1. School of Mechanical and Electronic Engineering, Nanjing Forestry University, Nanjing 210037, China.
2. Dept. of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing 210029, China.
- Publication Type:Journal Article
- Keywords:
alveolar bone;
fluid shear stress;
fluid-structure interaction;
porous structure
- MeSH:
Bone Remodeling;
Animals;
Tooth Movement Techniques;
Rats;
Alveolar Process/physiology*;
Stress, Mechanical;
Humans;
Biomechanical Phenomena;
Cancellous Bone/physiology*;
Shear Strength
- From:
West China Journal of Stomatology
2025;43(2):190-196
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVES:This study explores the differences in fluid flow within alveolar cancellous bone at various sites under orthodontic forces and elucidates the relationship between fluid shear stress and bone remodeling. These fin-dings lay the groundwork for understanding the biomechanical mechanisms of orthodontic tooth movement.
METHODS:Stress relaxation tests were performed on human alveolar bone samples to determine material parameters by using the Prony series. An inverse model of alveolar bone was then developed for numerical simulations of fluid-structure interactions to calculate fluid flow within cancellous bone. Meanwhile, a rat model of tooth movement was established to investigate variations in bone remodeling speeds across different regions.
RESULTS:The microstructural distribution of cancellous alveolar bone was similar in humans and rats. The bone volume fraction and trabecular thickness gradually decreased from root cervical region to root apical region, while the trabecular space gradually increased. Under the influence of orthodontic forces, fluid shear stress within cancellous bone showed spatial variability across different levels, with the highest shear stress occurring at the root apical region, ranging from 0 to 0.936 6 Pa. Additionally, the rat model of tooth movement indicated that bone remodeling occurred more rapidly at the root apical region.
CONCLUSIONS:Fluid stimulation has a remarkable effect on al-veolar bone remodeling, causing changes in the structure of alveolar bone and ultimately regulating the speed of structu-ral remodeling.
