Research progress in methods of acquisition, structure elucidation, and quality control of Chinese herbal polysaccharides.
10.1016/S1875-5364(25)60819-3
- Author:
Tingting WANG
1
;
Baojie ZHU
1
;
Jing ZHAO
2
;
Shaoping LI
3
Author Information
1. Joint Laboratory of Chinese Herbal Glycoengineering and Testing Technology, University of Macau & National Glycoengineering Research Center, Macao SAR 999078, China; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR 999078, China.
2. Joint Laboratory of Chinese Herbal Glycoengineering and Testing Technology, University of Macau & National Glycoengineering Research Center, Macao SAR 999078, China; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR 999078, China. Electronic address: jingzhao@um.edu.mo.
3. Joint Laboratory of Chinese Herbal Glycoengineering and Testing Technology, University of Macau & National Glycoengineering Research Center, Macao SAR 999078, China; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR 999078, China; Macao Centre for Testing of Chinese Medicine, University of Macau, Macao SAR 999078, China. Electronic address: spli@um.edu.mo.
- Publication Type:Review
- Keywords:
Chinese medicine;
Extraction and purification;
Polysaccharide;
Quality control;
Structural analysis
- MeSH:
Polysaccharides/isolation & purification*;
Drugs, Chinese Herbal/standards*;
Quality Control;
Medicine, Chinese Traditional;
Humans;
Molecular Structure
- From:
Chinese Journal of Natural Medicines (English Ed.)
2025;23(2):143-157
- CountryChina
- Language:English
-
Abstract:
The therapeutic efficacy of traditional Chinese medicine has been widely acknowledged due to its extensive history of clinical effectiveness. However, the precise active components underlying each prescription remain incompletely understood. Polysaccharides, as a major constituent of water decoctions-the most common preparation method for Chinese medicinals-may provide a crucial avenue for deepening our understanding of the efficacy principles of Chinese medicine and establishing a framework for its modern development. The structural complexity and diversity of Chinese herbal polysaccharides present significant challenges in their separation and analysis compared to small molecules. This paper aims to explore the potential of Chinese herbal polysaccharides efficiently by briefly summarizing recent advancements in polysaccharide chemical research, focusing on methods of acquisition, structure elucidation, and quality control.
