Expert consensus on diagnosis and treatment of intra-abdominal candidiasis in critically ill patients (2025 edition).
10.3760/cma.j.cn121430-20250301-00197
- Author:
Support PEKING UNIVERSITY CRITICAL CARE MEDICINE COMMITTEE OF CRITICAL CARE MEDICINE AND ORGAN
1
,
2
,
3
;
Technology CHINA ASSOCIATION FOR PROMOTION OF HEALTH SCIENCE AND
Author Information
1. Corresponding author: Li Shuangling, Department of Critical Care Medicine, Peking University First Hospital, Beijing 100034, Email: lishuangling888@hotmail.com; Chang Zhigang, Department of Critical Care Medicine of Beijing Hospital, National Center for Gerontology, Geriatrics Institute of Chinese Academy of Medical Sciences, Beijing 100730, Email: zhigangchang@
2. com; An Youzhong, Department of Critical Care Medicine, Peking University People's Hospital, Beijing 100044, Email: bjicu@
3. com.
- Publication Type:Consensus Development Conference
- MeSH:
Humans;
Critical Illness;
Intraabdominal Infections/therapy*;
Antifungal Agents/therapeutic use*;
Consensus;
Candidiasis/drug therapy*;
Critical Care;
Candidiasis, Invasive/diagnosis*
- From:
Chinese Critical Care Medicine
2025;37(6):509-526
- CountryChina
- Language:Chinese
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Abstract:
Intra-abdominal candidiasis (IAC) is the most common invasive candidiasis, with a high incidence among critically ill patients, which can significantly increase medical costs and affect prognosis. In order to standardize the diagnosis and treatment of IAC in critically ill patients, experts in related fields were organized by the Peking University Critical Care Medicine (PKUCCM), Committee of Critical Care Medicine and Organ Support, China Association for Promotion of Health Science and Technology organized experts in related fields to initiate and form a working group. Expert writers drafted the consensus based on evidence-based medical evidence. A committee composed of critical care physicians, infectious disease physicians, surgeons, dermatologists specializing in antifungal fields, and clinical pharmacists discussed and revised the consensus draft through a standardized process, and finally formulated this consensus. This consensus contains a total of 20 core recommendations, mainly focusing on the epidemiology, high-risk factors, diagnostic techniques and methods (including traditional microbiological culture techniques, clinical risk prediction tools, serological tests, molecular biological tests, and histopathological examinations) of IAC, diagnostic criteria, stratified treatment strategies, antifungal drug selection, control the sources of infection, combined treatment, de-escalation strategies, drug treatment courses, prognosis, and special types of IAC. The aim is to provide expert guidance for the standardized clinical diagnosis and treatment of IAC in critically ill patients, with a view to improving prognosis of patients.
