Annual review of clinical research on extracorporeal life support in 2024.
10.3760/cma.j.cn121430-20250107-00020
- Author:
Hongling ZHANG
1
;
Yuan YU
1
;
Zhongtao DU
2
,
3
;
Xiaojing ZOU
1
;
Xiaotong HOU
2
,
3
;
You SHANG
1
Author Information
1. Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.
2. Department of Cardiothoracic Intensive Care Unit, Anzhen Hospital, Capital Medical University, Beijing 100013, China. Corresponding author: Hou Xiaotong, Email: xt.hou@ccmu.edu.cn; Shang You, Email: you_shanghust@
3. com.
- Publication Type:English Abstract
- MeSH:
Humans;
Extracorporeal Membrane Oxygenation/methods*;
Shock, Cardiogenic/therapy*;
Cardiopulmonary Resuscitation;
Myocardial Infarction/therapy*
- From:
Chinese Critical Care Medicine
2025;37(4):317-323
- CountryChina
- Language:Chinese
-
Abstract:
The important studies in the field of extracorporeal life support (ECLS) in 2024 focused on the application of cardiac support technologies in acute myocardial infarction (AMI) with cardiogenic shock (CS): veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has not shown advantages in either short- or long-term outcomes and may increase the risk of bleeding and vascular complications; in contrast, micro-axial flow pumps demonstrate potential in improving mortality. The effects of veno-venous extracorporeal membrane oxygenation (V-V ECMO) combined with prone positioning on severe acute respiratory distress syndrome (ARDS) remain uncertain. The survival benefit of extracorporeal cardiopulmonary resuscitation (ECPR) in out-of-hospital cardiac arrest (OHCA) patients has been further validated. The potential benefits of extracorporeal carbon dioxide removal (ECCO2R) require further investigation. Additionally, new guidelines released in 2024 focus on Neurological monitoring and management during ECMO, as well as the Definition and management of right ventricular injury during veno-venous ECMO. ECMO management requires more refined strategies, including optimized oxygenation targets, anticoagulation, blood transfusion, and weaning strategies to improve patient outcomes.