Identifying purgative targets of sennoside A via in situ biotransformation of prodrug-based probes.
- Author:
Zhen LIU
1
;
Xinyue GENG
1
;
Xinyue LIU
1
;
Mengru LI
1
;
Xiang LI
1
;
Zhixin ZHANG
1
;
Gan LUO
1
;
Ying WANG
1
;
Xiaoyan GAO
1
Author Information
- Publication Type:Journal Article
- From: Journal of Pharmaceutical Analysis 2025;15(4):101078-101078
- CountryChina
- Language:English
- Abstract: •A strategy for in situ metabolically synthesized active drug-based probes was proposed.•The potential purgative targets of SA were successfully hooked and identified.•The work provided a new insight for studying the direct targets of unstable active drugs.
