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CRISPR-based screening pinpoints H2AZ1 as a driver of senescence in human mesenchymal stem cells.

Author: Ming-Heng LI ¹ ; Xiaoyu JIANG ² ; Yaobin JING ² ; Kaowen YAN ² ; Shi-Jia BI ¹ ; Si WANG ³ ; Shuai MA ² ; Guang-Hui LIU ² ; Weiqi ZHANG ⁴ ; Shuhui SUN ² ; Jing QU ¹
Author Information

1. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
2. State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
3. Advanced Innovation Center for Human Brain Protection and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China.
4. CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China.
Publication Type:Journal Article
From: Protein & Cell 2025;16(4):296-305
CountryChina
Language:English