Therapeutic potential of extracellular vesicles in neurological diseases.
10.12122/j.issn.1673-4254.2025.09.24
- Author:
Qingfeng DU
1
;
Chao YANG
2
;
Xueqing XIA
1
;
Ting WANG
1
Author Information
1. School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.
2. General Hospital of Southern Theatre Command, Guangzhou 510010, China.
- Publication Type:English Abstract
- Keywords:
extracellular vesicles;
medicated therapy;
neurological disorders;
treatment
- MeSH:
Extracellular Vesicles;
Humans;
Nervous System Diseases/therapy*;
Medicine, Chinese Traditional
- From:
Journal of Southern Medical University
2025;45(9):2046-2054
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular vesicles (EVs), nanoscale lipid bilayer vesicles actively secreted by organisms into the extracellular environment, are rich in specific bioactive substances, such as proteins, genetic materials and lipids. These vesicles are involved in intercellular interactions and can pass through the blood-brain barrier, and may thus potentially serve as important biological substances for treatment of neurological diseases. In this review, we summarize the biological origin of EVs and their therapeutic potential in neurological diseases, expound the possibility of EV-based treatment of neurological diseases using traditional Chinese medicine, and discuss the challenges and prospects of researches of EVs for the treating neurological diseases.
