Intraoperative renal collecting system damage increases risks of ipsilateral upper urinary tract stones after partial nephrectomy: a 1∶2 propensity-matched case-control study.
10.12122/j.issn.1673-4254.2025.09.08
- Author:
Yanzhong LIU
1
;
Run ZHU
2
;
Yuzhu LI
2
;
Xin MA
2
;
Haixing MAI
2
Author Information
1. Medical School of Chinese PLA, Beijing 100083, China.
2. Department of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing 100039, China.
- Publication Type:Journal Article
- Keywords:
partial nephrectomy;
renal collecting system;
urolithiasis
- MeSH:
Humans;
Nephrectomy/methods*;
Retrospective Studies;
Risk Factors;
Male;
Female;
Case-Control Studies;
Middle Aged;
Aged;
Kidney Neoplasms/surgery*;
Adult;
Intraoperative Complications;
Kidney Tubules, Collecting/injuries*;
Propensity Score;
Incidence;
Kidney Calculi/etiology*;
Urinary Calculi/epidemiology*
- From:
Journal of Southern Medical University
2025;45(9):1880-1888
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVES:To investigate the incidence of ipsilateral upper urinary tract stones after partial nephrectomy and its risk factors.
METHODS:We retrospectively analyzed baseline patient characteristics (age, gender, and body mass index), smoking, alcohol consumption, comorbidities (hypertension, diabetes, hypertriglyceridemia, hyperuricemia, and cardiovascular diseases), preoperative tumor conditions (tumor diameter, multiple foci, location, hemorrhage, necrosis, cystic changes, and endophytic growth), preoperative glomerular filtration rate and intraoperative factors (renal collecting system damage, ischemia time, operation time, surgical approach, and estimated intraoperative blood loss) to identify the risk factors for ipsilateral upper urinary tract stones following partial nephrectomy in our center.
RESULTS:The overall incidence of upper urinary tract stones following partial nephrectomy was 7.80% (112/1435). The incidence of ipsilateral upper urinary tract stones was significantly higher than those of contralateral stones (4.95% vs 1.46%, P<0.001) and bilateral stones (4.95% vs 1.39%, P<0.001). Intraoperative damage to the renal collecting system was identified as a significant risk factor for ipsilateral upper urinary tract stones (OR=4.550, 95% CI: 2.237-9.252, P<0.001). Diabetes was a probable risk factor for secondary ipsilateral upper urinary tract stones after partial nephrectomy (OR=2.419, 95% CI: 0.973-6.012, P=0.057).
CONCLUSIONS:The incidence of ipsilateral upper urinary tract stones after partial nephrectomy is higher than that of contralateral and bilateral stones. Intraoperative renal collecting system damage is a risk factor for secondary ipsilateral upper urinary tract stones after partial nephrectomy.
