Epidemiological survey of osteoporosis in Beijing over the past decade: a single-center analysis of dual-energy X-ray absorptiometry scans from 30 599 individuals.
10.12122/j.issn.1673-4254.2025.03.01
- Author:
Ying ZHOU
1
;
Danyang ZHANG
2
;
Lifan WU
3
;
Guishan WANG
1
;
Jiedan MU
1
;
Chengwen CUI
1
;
Xiuxiu SHI
1
;
Jige DONG
4
;
Yu WANG
2
;
Wangli XU
2
;
Xiao LI
1
Author Information
1. Department of Rehabilitation Medicine, Senior Department of Orthopedics, Fourth Medical Center of PLA General Hospital, National Clinical Research Center for Orthopedics, Sports Medicine & Rehabilitation, Beijing 100048, China.
2. Research Center for Statistical Science, School of Statistics, Renmin University of China, Beijing 100872, China.
3. School of Sports Rehabilitation, Tianjin University of Physical Education, Tianjin 301617, China.
4. Rehabilitation Center, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China.
- Publication Type:Journal Article
- Keywords:
bone mineral density;
dual-energy X-ray;
epidemiology;
osteoporosis
- MeSH:
Humans;
Bone Density;
Absorptiometry, Photon;
Male;
Female;
Retrospective Studies;
Osteoporosis/diagnostic imaging*;
Adult;
Middle Aged;
Lumbar Vertebrae/diagnostic imaging*;
China/epidemiology*;
Femur Neck/diagnostic imaging*;
Aged;
Beijing/epidemiology*;
Young Adult
- From:
Journal of Southern Medical University
2025;45(3):443-452
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVES:To analyze bone mass distribution and the factors affecting bone mass in a general Chinese Han cohort undergoing physical examinations at our center.
METHODS:We retrospectively collected the data of bone mineral density (BMD) measurements from 30 599 healthy Han Chinese adults (age≥20 years) who underwent dual-energy X-ray absorptiometry scans at our hospital from July, 2013 to July, 2023. Basic parameters including height, body weight, and gender were recorded, and descriptive statistics and correlation analyses were performed using R software.
RESULTS:In this cohort, the male individuals had a mean peak BMD of 1.00±0.12 g/cm2 in the lumbar vertebrae, 0.94±0.14 g/cm2 in the femoral neck, and 0.99±0.13 g/cm2 in the total hip, significantly higher than the values in the female individuals [0.99±0.12 g/cm2 in the lumbar vertebrae (P=0.022), 0.79±0.11 g/cm2 in the femoral neck (P<0.001), and 0.88±0.11 g/cm2 in the total hip (P<0.001)]. In the overall cohort, the BMD values of the lumbar spine and femur decreased with age after reaching their peak levels. There was a positive correlation between BMD value and body mass index (BMI) in both male and female individuals. The 2013-2014 period recorded the lowest BMD values in the lumbar, hip, and femoral neck, which tended to increase steadily in the following years (2015-2023).
CONCLUSIONS:Our data suggest that the BMD values vary among different populations, and future multi-center studies using more accurate BMD detection technology are warranted to capture the variation patterns of BMD with demographic characteristics of specific populations.
