Targeting stiff stroma by neutralizing LOX-mediated matrix crosslinking in pancreatic cancer.

Author: Shan ZHANG ¹ ; Zhiwei CAI ² ; Luju JIANG ¹ ; Shuqi CAI ¹ ; Zheqi WENG ¹ ; Shuheng JIANG ¹
Author Information

1. State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.
2. Department of General Surgery, Pancreatobiliary Surgery Center, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.
Publication Type:Letter
Keywords: Elastic modulus; Extracellular matrix; Pancreatic ductal adenocarcinoma; Stiffness
From: Acta Pharmaceutica Sinica B 2025;15(5):2783-2786
CountryChina
Language:English