Microglial APOE4 promotes neuron degeneration in Alzheimer's disease through inhibition of lipid droplet autophagy.
10.1016/j.apsb.2024.10.009
- Author:
Meng MAO
1
;
Xiwen MA
1
;
Xiaochuan WANG
2
;
Jianping YE
1
Author Information
1. Metabolic Disease Research Center, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450052, China.
2. Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
- Publication Type:Journal Article
- Keywords:
ACSL1;
APOE4;
Alzheimer's disease (AD);
Lipid droplets;
Microglia
- From:
Acta Pharmaceutica Sinica B
2025;15(1):657-660
- CountryChina
- Language:English