Western Pacific Region Index Medicus

DiPTAC: A degradation platform via directly targeting proteasome.

Author: Yutong TU ¹ ; Qian YU ² ; Mengna LI ¹ ; Lixin GAO ³ ; Jialuo MAO ¹ ; Jingkun MA ¹ ; Xiaowu DONG ⁴ ; Jinxin CHE ⁴ ; Chong ZHANG ² ; Linghui ZENG ² ; Huajian ZHU ² ; Jiaan SHAO ² ; Jingli HOU ⁵ ; Liming HU ⁶ ; Bingbing WAN ⁶ ; Jia LI ¹ ; Yubo ZHOU ¹ ; Jiankang ZHANG ²
Author Information

1. Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan 528400, China.
2. School of Medicine, Hangzhou City University, Hangzhou 310015, China.
3. School of Life ScienceS and Health Engineering, Jiangnan University, Wuxi 214122, China.
4. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
5. Instrumental AnalysiS Center of Shanghai Jiao Tong University, Shanghai 200240, China.
6. Key Laboratory of SystemS Biomedicine (Ministry of Education), Shanghai Center for SystemS Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Publication Type:Journal Article
Keywords: DiPTAC; E3; PROTAC; Proteasome; Targeted protein degradation
From: Acta Pharmaceutica Sinica B 2025;15(1):661-664
CountryChina
Language:English