Rare giant solitary vagus neurofibroma of the neck: a case report and literature review.
10.13201/j.issn.2096-7993.2025.12.016
- Author:
Liaoliang HAO
1
;
Xiangxiang WANG
1
;
Jingxuan SHI
1
;
Lu WANG
1
;
Tianfeng DANG
1
;
Xiangyun QIAO
1
;
Qianqian ZHAO
1
;
Leping LIANG
1
Author Information
1. Department of Otolaryngology Head and Neck Surgery，the Second Affiliated Hospital of Air Force Medical University，Xi'an，710038，China.
- Publication Type:English Abstract
- Keywords:
neurilemmoma;
neurofibroma;
neurofibromatosis type Ⅰ;
vagus nerve
- MeSH:
Humans;
Female;
Adult;
Neurofibroma;
Vagus Nerve/pathology*;
Neck;
Cranial Nerve Neoplasms
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2025;39(12):1192-1196
- CountryChina
- Language:Chinese
-
Abstract:
Neurofibromas are benign peripheral nerve sheath tumors. It is more common in neurofibromatosis type Ⅰ. However, isolated vagal nerve neurofibroma（VNN） of the neck is extremely rare, and only a few case reports have been reported. Its etiology and pathogenesis are not clear. The diagnosis is mainly based on pathological examination and immunohistochemistry, and surgical resection is the main treatment. This study reports a rare case of giant solitary vagus neurofibroma in the neck. The patient was a 29-year-old female who was found to have a mass on the right side of the neck by physical examination, which was considered to be a vagus nerve tumor by neck ultrasound and imaging examination. The tumor was completely removed during the operation, with the size of about 10.0 cm×2.5 cm, and the patient had no special discomfort. Postoperative pathology and immunohistochemistry confirmed neurofibroma. After surgery, the patient had right vocal cord paralysis, hoarseness, choking and paroxysmal cough. After swallowing function training and voice rehabilitation treatment in the department, the patient recovered satisfactorily. There was no complication and recurrence during the follow-up of 1 year. This article reviews the literature to improve the diagnosis and treatment of solitary vagus neurofibroma in the neck by combining its medical history, imaging features, pathology and immunohistochemistry, and surgical treatment.
