One case of hypopharyngeal dedifferentiated liposarcoma.
10.13201/j.issn.2096-7993.2025.11.018
- Author:
Maolin YANG
1
;
Yangling DU
1
;
Jun ZHENG
1
;
Jinshu MA
2
;
Jichao SHA
1
Author Information
1. Department of Otolaryngology Head and Neck Surgery，China-Japan Union Hospital of Jilin University，Changchun，130033，China.
2. Department of Pathology，China-Japan Union Hospital of Jilin University.
- Publication Type:English Abstract
- Keywords:
dedifferentiated liposarcoma;
pharynx;
surgical treatment
- MeSH:
Humans;
Male;
Liposarcoma/diagnosis*;
Hypopharyngeal Neoplasms/diagnosis*;
Middle Aged;
Hypopharynx;
Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2025;39(11):1099-1102
- CountryChina
- Language:Chinese
-
Abstract:
Differentiated liposarcoma is a rare connective tissue malignancy in adults that mostly occurs in the extremities and retroperitoneum, with a tendency to aggressiveness and recurrence, and the ten-year survival rate of about 10%. Clinically, dedifferentiated liposarcoma of the pharynx has been reported to be rare abroad and only one case has been reported in China. Clinical symptoms are mainly foreign body sensation in the pharynx, which can be easily misdiagnosed as benign tumors. Pathological diagnosis is the main examination tool for this kind of disease, and immunohistochemistry and FISH test can help to differentiate it from other tumors. This article presents a case of a male patient with dedifferentiated liposarcoma of the hypopharynx, who had a foreign body sensation in the pharynx for more than 1 month, and underwent supported laryngoscopic pharyngeal lesion resection after completing the preoperative relevant examinations and postoperative radiation therapy, with postoperative pathology returned as dedifferentiated liposarcoma. The present postoperative follow-up was 12 months without recurrence. Therefore, accurate diagnosis and timely treatment are extremely important for the prognosis of this disease.
