Palatovaginal canal can be the origin of nasopharyngeal fibrovascular tumors.
10.13201/j.issn.2096-7993.2025.08.011
- Author:
Zhuofu LIU
1
;
Huankang ZHANG
1
;
Qiang LIU
1
;
Han LI
1
;
Jingjing WANG
1
;
Huan WANG
1
;
Dehui WANG
1
Author Information
1. Department of Otolaryngology，Head and Neck Surgery，Affiliated Eye，Ear，Nose and Throat Hospital，Shanghai，200031，China.
- Publication Type:Journal Article
- Keywords:
alatovaginal canal;
igh-resolution CT;
juvenile nasopharyngeal angiofibroma;
riginal site;
terygoid canal
- MeSH:
Humans;
Nasopharyngeal Neoplasms/pathology*;
Retrospective Studies;
Angiofibroma/pathology*;
Neoplasm Invasiveness;
Pterygopalatine Fossa/pathology*;
Female;
Magnetic Resonance Imaging;
Male;
Tomography, X-Ray Computed;
Adolescent
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2025;39(8):754-762
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the anatomic origin of juvenile nasopharyngeal angiofibroma（JNA） through radiologic analysis of tumor invasion patterns, providing insights into tumor etiology and surgical recurrence prevention. Methods:This retrospective cohort study included primary JNA cases at the Department of Otorhinolaryngology, Eye and ENT Hospital of Fudan University from March 2015 to September 2024. All patients underwent preoperative high-resolution CT（HRCT） scans, and some underwent enhanced magnetic resonance imaging. The study retrospectively analyzed the patients' imaging data to examine tumor invasion into the pterygopalatine fossa and the vidian canal. These sites were categorized into non-invaded, partially invaded, and completely invaded for the pterygopalatine fossa and the vidian canal. The study analyzed the proportions of invasion at these sites to further speculate on the origin of JNA. Results:A total of 105 JNA patients were included in the study. Among them, 100% of the patients had complete tumor invasion in the pterygopalatine fossa. For the vidian canal, the proportions of complete invasion, partial invasion, and non-invasion were 54.3%, 27.6%, and 18.1%, respectively. As the staging of JNA tumors increased, the proportion of vidian canal invasion also increased. Conclusion:Our evidence suggests that the pterygopalatine fossa, rather than the vidian canal, might be the likely origin of JNA, which is enlightening for the study of the etiological mechanisms of JNA.
