A case report of giant neurofibromatosis of maxillofacial, neck and chest was treated by multidisciplinary cooperation.
10.13201/j.issn.2096-7993.2025.04.015
- Author:
Shuzhen CHEN
1
;
Leifeng LIU
1
;
Haitao QIU
1
;
Jun YAO
1
;
Qizhu CHEN
1
;
Mei XU
2
Author Information
1. Otolaryngology Center，Affiliated Hospital of Guangdong Medical University，Zhanjiang，524001，China.
2. Clinical Skills Training Center，the First Clinical College of Medicine，Guangdong Medical University.
- Publication Type:English Abstract
- Keywords:
cutaneous neurofibroma;
neurofibromatosis type 1;
surgical treatment
- MeSH:
Humans;
Head and Neck Neoplasms/surgery*;
Neck;
Neurofibromatoses;
Neurofibromatosis 1/surgery*;
Thoracic Neoplasms/surgery*
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2025;39(4):376-378
- CountryChina
- Language:Chinese
-
Abstract:
Neurofibromatosis Type 1 （NF1） is an autosomal dominant hereditary neurological disorder. One of the typical manifestations of NF1 is neurofibroma, which can develop gradually over time. When the volume exceeds 100 cm², it is referred to as giant neurofibroma, representing a tumor-like proliferation of Schwann cells within the nerve fiber sheath. The Department of Otolaryngology at the Affiliated Hospital of Guangdong Medical University received a rare case involving a patient with giant neurofibromatosis affecting the maxillofacial region, neck, and chest. The patient underwent successful surgical treatment with the collaboration of various medical disciplines.
