Clinical analysis of 78 cases of refractory pharyngeal ulcers.
10.13201/j.issn.2096-7993.2025.04.013
- Author:
Jingyuan MA
1
;
Guangke WANG
1
;
Jing LI
1
;
Yanzi ZANG
1
Author Information
1. Department of Otorhinolaryngology,Henan Provincial People's Hospital,Zhengzhou University People's Hospital,Zhengzhou,450003,China.
- Publication Type:Journal Article
- Keywords:
laryngeal fungal infection;
laryngeal nucleus;
lymphoma;
pharyngeal ulcer
- MeSH:
Humans;
Male;
Female;
Retrospective Studies;
Middle Aged;
Adult;
Aged;
Pharyngeal Diseases/pathology*;
Young Adult;
Ulcer/pathology*;
Adolescent;
Aged, 80 and over
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2025;39(4):362-375
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical characteristics, treatment methods, and prognosis of refractory pharyngeal ulcers. Methods:A retrospective analysis was conducted on the clinical manifestations, laryngoscopic features, laboratory tests, histopathological examinations, and treatments of 78 patients diagnosed with refractory pharyngeal ulcers. Results:There was no significant difference in the proportion of males-to-females in benign lesions, while males were significantly more prevalent in cases of malignant lesions. Seven distinct pathological types of pharyngeal ulcers were identified, with the most common being simple inflammatory ulcers(18 cases), followed by tuberculosis(16 cases), fungi(15 cases), lymphoma(14 cases), squamous cell carcinoma(10 cases), Behcet's disease(3 cases), and myelosarcoma(2 cases). Conclusion:The clinical manifestations and lesions associated with refractory pharyngeal ulcers are diverse. A clear diagnosis should be established based on a systematic and comprehensive medical history, specialized examinations, and additional tests to avoid misdiagnosis and mistreatment. Laryngoscopy and histopathological examinations are essential for identifying the type of lesion and guiding appropriate treatment.