Clinical characteristics of sudden sensorineural hearing loss patients accompanying diabetes mellitus and efficacy analysis via propensity score matchin.
10.13201/j.issn.2096-7993.2025.03.004
- Author:
Xiaohui ZHAO
1
;
Suwei MA
1
;
Qingxuan CUI
1
;
Jiao ZHANG
2
;
Dayong WANG
2
;
Qiuju WANG
2
Author Information
1. Binzhou Medical College Department of Hearing and Speech Rehabilitation，Yantai，264003，China.
2. Department of Audiology and Vestibular Medicine，Senior Department of Otolaryngology Head and Neck Surgery，the Sixth Medical Center of Chinese PLA General Hospital.
- Publication Type:Journal Article
- Keywords:
clinical characteristic;
diabetes;
efficacy;
sudden sensorineural hearing loss
- MeSH:
Humans;
Propensity Score;
Retrospective Studies;
Hearing Loss, Sensorineural/therapy*;
Hearing Loss, Sudden/therapy*;
Middle Aged;
Diabetes Mellitus;
Male;
Female;
Prognosis;
Adult;
Logistic Models;
Diabetes Complications;
Aged;
Treatment Outcome
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2025;39(3):207-213
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize and analyze the clinical characteristics of patients with sudden sensorineural hearing loss（SSHL） accompanying diabetes mellitus, to explore whether diabetes affects the treatment outcomes during hospitalization, and to identify the factors influencing the efficacy of SSHL patients with diabetes. Methods:A retrospective analysis was conducted on clinical data from 939 patients with SSHL. The baseline characteristics, and onset conditions of the diabetes group（79 cases） and the non-diabetes group（860 cases） were compared. Propensity score matching（PSM） was applied in a 1︰ 2 ratio to match initial hearing levels with baseline characteristics such as age, sex, and BMI, resulting in 73 diabetes cases and 144 non-diabetes cases for treatment efficacy comparison. For the analysis of prognostic factors, a logistic regression model was established based on the treatment outcomes of 217 patients with SSHL. Results:The proportion of SSHL patients accompanying diabetes was 8.40%（79/939）. Compared to non-diabetic patients, those with diabetes were older（median age of 53 years in the diabetes group and 39 years in the non-diabetes group） and had a higher proportion of hypertension（43.04% vs 12.67%）, with significant difference observed（P<0.05）. After PSM, the treatment efficacy during hospitalization was better in the diabetes group than in the non-diabetes group（58.90% vs 47.92%）, although the difference was not statistically significant（P>0.05）. The prognosis of patients with SSNHL accompanied by diabetes was analyzed using a multivariate logistic regression model that included age, HDL-C, and INR as variables; however, no statistically significant differences were found（P>0.05）. Conclusion:Patients with SSHL accompanying diabetes are generally older with a higher incidence of hypertension. The presence of diabetes does not affect the treatment outcomes during hospitalization.
