Application progress of collagen membranes in oral medicine.
10.11817/j.issn.1672-7347.2025.240642
- Author:
Yiqin WANG
1
,
2
,
3
;
Junliang WEN
1
;
Xinhang YU
1
;
Jun CHEN
1
;
Wenjie LI
1
,
4
Author Information
1. Hunan Engineering Research Center for Oral Digital Intelligence and Personalized Medicine; Hunan Key Laboratory of Oral Health Research; Hunan 3D Printing Engineering Research Center of Oral Care; Hunan Clinical Research Center of Oral Major Diseases and Oral Health; WANG Songling Academician Workstation for Oral-maxillofacial and Regenerative Medicine; Xiangya School of Stomatology, Central South University, Changsha
2. wyq0819jqq@
3. com.
4. liwenj@csu.edu.cn.
- Publication Type:English Abstract
- Keywords:
bone defects;
bone regeneration;
collagen membrane;
gustatory sweating syndrome;
keratinized mucosa;
maxillary sinus perforation;
periodontitis;
pulp regeneration
- MeSH:
Collagen/therapeutic use*;
Humans;
Biocompatible Materials/chemistry*;
Membranes, Artificial;
Oral Medicine/methods*;
Tissue Engineering/methods*
- From:
Journal of Central South University(Medical Sciences)
2025;50(6):1088-1098
- CountryChina
- Language:Chinese
-
Abstract:
Collagen membrane has attracted much attention from researchers due to its excellent properties such as wide source, degradable absorption, and low immunogenicity. However, they are limited by poor mechanical stability and rapid degradation. To enhance their physicochemical properties and biological functions, researchers have developed various strategies, including cross-linking, incorporation of growth factors or drugs, combination with other biomaterials, optimization of composition and structure, and substitution with marine-derived collagen. These advances aim to expand the clinical applications of collagen membranes in oral medicine. With the urgent demand for high-performance biomaterials in oral medicine, summarizing recent progress on collagen membranes provides valuable insights into their mechanisms, clinical efficacy, and limitations, offering reference for optimized design and broader clinical use. Furthermore, further trends may include integrating advanced manufacturing technologies to develop personalized collagen membranes, which could significantly improve therapeutic outcomes in oral diseases.
