Characteristics of the amygdala and its subregions in premenstrual syndrome/premenstrual dysphoric disorder patients.
10.11817/j.issn.1672-7347.2025.240526
- Author:
Ming CHENG
1
,
2
,
3
;
Baoyi LI
4
;
Zhen ZHANG
1
,
3
,
5
;
Zhaoshu JIANG
1
;
Jie YANG
1
;
Peng JIANG
6
;
Zhonghao YUAN
7
Author Information
1. Yang Sheng College of Traditional Chinese Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang
2. chengming202310@
3. com.
4. College of Medical Imaging, Changsha Medical University, Changsha
5. gzzyy_zz@
6. First Clinical College, Changsha Medical University, Changsha
7. College of Traditional Chinese Medicine, Changsha Medical University, Changsha 410219, China.
- Publication Type:Review
- Keywords:
amygdala;
brain networks;
connectivity characteristics;
neural circuits;
premenstrual dysphoric disorder;
premenstrual syndrome
- MeSH:
Humans;
Amygdala/diagnostic imaging*;
Female;
Premenstrual Dysphoric Disorder/pathology*;
Premenstrual Syndrome/pathology*;
Emotions/physiology*;
Magnetic Resonance Imaging
- From:
Journal of Central South University(Medical Sciences)
2025;50(3):492-500
- CountryChina
- Language:English
-
Abstract:
Premenstrual dysphoric disorder (PMDD) is considered a severe form of premenstrual syndrome (PMS). As a key brain region involved in emotional regulation and stress responses, the amygdala has been implicated in the pathogenesis of PMS/PMDD. The amygdala is composed of multiple subregions, each playing distinct roles in emotion, memory, and stress responses, and forms complex brain areas. Summarizing the interconnections among amygdala, subregions and their connectivity with external areas, and exploringt the neuroimaging characteristics of the amygdala, as well as changes in its neural circuits and brain networks in these patients, will help provide a theoretical foundation for targeted modulation of amygdala function in the treatment of PMS/PMDD.
