Value of spinal high temporal/high spatial resolution CE-MRA in the diagnosis of spinal dural arteriovenous fistulas.
10.11817/j.issn.1672-7347.2024.240391
- Author:
Yihang SU
1
,
2
;
Jilin NIE
3
;
Bin CHEN
3
;
Shuai YANG
3
;
Changyong CHEN
3
;
Weihua LIAO
3
;
Qing ZHAO
4
Author Information
1. Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, China. suyihang159@
2. com.
3. Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, China.
4. Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, China. zq570153364@foxmail.com.
- Publication Type:Journal Article
- Keywords:
contrast- enhanced magnetic resonance angiography;
digital subtraction angiography;
feeding arteries;
high temporal/high spatial resolution;
magnetic resonance imaging;
sensitivity;
spinal dural arteriovenous fistulas
- MeSH:
Humans;
Central Nervous System Vascular Malformations/diagnosis*;
Male;
Female;
Retrospective Studies;
Middle Aged;
Magnetic Resonance Angiography/methods*;
Angiography, Digital Subtraction/methods*;
Aged;
Adult;
Sensitivity and Specificity;
Contrast Media;
Magnetic Resonance Imaging/methods*
- From:
Journal of Central South University(Medical Sciences)
2024;49(12):1927-1933
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:Digital subtraction angiography (DSA) is the current gold standard for diagnosing spinal dural arteriovenous fistulas (SDAVF). However, DSA is invasive and associated with risks such as ionizing radiation and iodine contrast allergy. Contrast-enhanced magnetic resonance angiography (CE-MRA) with high temporal/high spatial resolution allows dynamic multiphase contrast-enhanced imaging with excellent detail. This study aims to evaluate the diagnostic value of spinal CE-MRA with high temporal/high spatial resolution for SDAVF.
METHODS:Clinical data were retrospectively collected from patients who underwent both conventional spinal MRI and high temporal/high spatial resolution CE-MRA at Xiangya Hospital between January 1, 2021, and January 1, 2024, and who subsequently underwent DSA or surgery within 90 days. Two experienced radiologists independently reviewed all conventional MRI and CE-MRA images. The sensitivity and specificity of conventional MRI and CE-MRA for diagnosing SDAVF were calculated against the gold standard DSA findings. Kappa statistics were used to evaluate the consistency of MRI and CE-MRA compared to DSA. The diagnostic value was further assessed by calculating the area under curve (AUC) of the receiver operating characteristic (ROC).
RESULTS:A total of 60 patients were included, of whom 47 were diagnosed with SDAVF and 13 were not. Conventional MRI had 3 false negatives and 1 false positive; CE-MRA had 2 false positives and 0 false negative. The sensitivity and specificity of conventional MRI were 93.62% and 92.31%, respectively. CE-MRA demonstrated 100% sensitivity and 84.62% specificity. The main cause of false positives was the misidentification of posterior spinal arteries as feeding arteries. CE-MRA clearly displayed most feeding arteries, and the accuracy of fistula localization was 74.47% (35/47). Kappa values for conventional MRI and CE-MRA were 0.814 and 0.896, respectively (both P<0.001), indicating good agreement, with CE-MRA outperforming conventional MRI. The AUCs for diagnosing SDAVF were 0.930 for conventional MRI and 0.923 for CE-MRA (both P<0.05).
CONCLUSIONS:Spinal CE-MRA with high temporal/high spatial resolution is a reliable, non-invasive imaging technique with high sensitivity for diagnosing SDAVF. It can clearly visualize feeding arteries and provides valuable preoperative diagnostic and localization information to support DSA or surgical planning.
