Topic Modeling Analysis of Chinese Medicine Literature on Gastroesophageal Reflux Disease: Insights into Potential Treatment.
10.1007/s11655-024-3800-y
- Author:
Jia-Nan QIAN
1
;
Yan-Lan KANG
2
;
You-Cheng HE
3
;
Hong-Yi HU
4
Author Information
1. Department of Gastroenterology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
2. Institute of AI and Robotics, Academy for Engineering & Technology, Fudan University, Shanghai, 200433, China.
3. Clinical Research Center, Longhua Hospital, Shanghai, 200032, China.
4. Department of Gastroenterology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. hongyihu2003@shutcm.edu.cn.
- Publication Type:Journal Article
- Keywords:
BERTopic;
Chinese medicine;
gastroesophageal reflux disease;
prescription;
topic modeling
- MeSH:
Humans;
Gastroesophageal Reflux/drug therapy*;
Medicine, Chinese Traditional/methods*;
Drugs, Chinese Herbal/therapeutic use*;
Models, Theoretical
- From:
Chinese journal of integrative medicine
2024;30(12):1128-1136
- CountryChina
- Language:English
-
Abstract:
OBJECTIVE:To analyze Chinese medicine (CM) prescriptions for gastroesophageal reflux disease (GERD), we model topics on GERD-related classical CM literature, providing insights into the potential treatment.
METHODS:Clinical guidelines were used to identify symptom terms for GERD, and CM literature from the database "Imedbooks" was retrieved for related prescriptions and their corresponding sources, indications, and other information. BERTopic was applied to identify the main topics and visualize the data.
RESULTS:A total of 36,207 entries are queried and 1,938 valid entries were acquired after manually filtering. Eight topics were identified by BERTopic, including digestion function abate, stomach flu, respiratory-related symptoms, gastric dysfunction, regurgitation and gastrointestinal dysfunction in pediatric patients, vomiting, stroke and alcohol accumulation are associated with the risk of GERD, vomiting and its causes, regurgitation, epigastric pain, and symptoms of heartburn.
CONCLUSIONS:Topic modeling provides an unbiased analysis of classical CM literature on GERD in a time-efficient and scale-efficient manner. Based on this analysis, we present a range of treatment options for relieving symptoms, including herbal remedies and non-pharmacological interventions such as acupuncture and dietary therapy.
