Advances in Research and Application of Bio-based Microsphere Adsorbents in Blood Adsorption.
10.12455/j.issn.1671-7104.240649
- Author:
Xinran GUO
1
;
Yuewei NIU
1
;
Weikang CHEN
1
;
Hua ZOU
1
;
Zhenggen YANG
1
;
Suhua XU
2
Author Information
1. Guangzhou Koncen BioScience Co., Ltd., Guangdong Provincial Key Laboratory of Hemoadsorption Technology, Guangzhou,
2. Guangdong Medical Devices Quality Surveillance and Test Institute, NMPA Key Laboratory for Extracorporeal Circulation Devices, Guangzhou Key Laboratory of Biomedical Blood Purification Materials Research and Development, Guangzhou,
- Publication Type:English Abstract
- Keywords:
bio-based materials;
blood adsorption;
microsphere adsorbents
- MeSH:
Microspheres;
Adsorption;
Humans
- From:
Chinese Journal of Medical Instrumentation
2025;49(5):527-533
- CountryChina
- Language:Chinese
-
Abstract:
One of the key components of adsorbents for blood purification is the microsphere adsorbent. Microsphere adsorbents should meet the following requirements: stable physical and chemical structures, easy for functional modification to endow the adsorbents with specific adsorption functions or characteristics, with good biocompatibility and with low non-specific adsorption, as well as with enough mechanical strength. Microsphere adsorbents prepared from polysaccharide bio-based materials fulfill the above requirements and have been widely used in the field of blood adsorption. In this article, adsorbents prepared from polysaccharide bio-based materials such as cellulose, agarose, alginate, as well as adsorbents prepared from the aforementioned materials and carbon materials and the application of the said bio-based adsorbents in blood adsorption is reviewed. The future development is also discussed, aiming to provide guidance and reference for the preparation, functional modification and application research of bio-based adsorbents for blood adsorption.
