Power Spectral Parameterization of the EEG Alpha for Analgesia.
10.12455/j.issn.1671-7104.240736
- Author:
Haidi WU
1
;
Yan WANG
2
;
Chang'an A ZHAN
1
;
Hongfei ZHANG
2
;
Feng YANG
1
Author Information
1. School of Biomedical Engineering, Southern Medical University, Guangzhou,
2. Department of Anesthesiology, Zhujiang Hospital, Southern Medical University, Guangzhou,
- Publication Type:Journal Article
- Keywords:
analgesia;
electroencephalography (EEG);
power spectra;
power spectral parameterization
- MeSH:
Humans;
Electroencephalography/methods*;
Female;
Adult;
Alpha Rhythm;
Pregnancy;
Young Adult;
Analgesia, Epidural
- From:
Chinese Journal of Medical Instrumentation
2025;49(5):494-500
- CountryChina
- Language:Chinese
-
Abstract:
Neural oscillatory changes play a critical role in pain and analgesia research. Previous studies on pain-related neural oscillations have primarily utilized electroencephalogram (EEG) power spectral analysis, revealing a strong correlation between alpha ( α) power and subjective pain perception. However, alpha power may be influenced by the baseline of the power spectrum, making it difficult to accurately capture the true changes in alpha oscillations. This study employed power spectral analysis and further applied a power spectral parameterization method, which decomposed the power spectrum into periodic and aperiodic components, to compare EEG α power in 50 primiparous women who underwent severe pain during the first stage of labor before and after epidural analgesia. The results indicated no significant differences in α power between pre- and post-analgesia conditions. However, following power spectral parameterization, the aperiodic component of the EEG significantly decreased after analgesia, whereas the periodic component of α power showed a significant increase. This study not only validates the effectiveness and validity of the power spectral parameterization method in analgesia research but also uncovers the differential regulatory mechanism by which analgesia modulates the periodic and aperiodic components of α oscillations.
