Application Research of mDIXON-Quant Quantitative T2* Values and FF Values in Cervical Intervertebral Disc Degeneration.
10.12455/j.issn.1671-7104.240348
- Author:
Peng LIU
1
;
Meichen NIU
2
;
Hong LIU
3
Author Information
1. Department of CT/MR, Fuyang People's Hospital, Fuyang,
2. The Thirteenth Ward, the Third People's Hospital of Fuyang, Fuyang,
3. Department of Rehabilitation, the Fifth People's Hospital of Fuyang, Fuyang,
- Publication Type:Journal Article
- Keywords:
FF values;
T2* values;
cervical spine;
intervertebral disc degeneration;
mDIXON-Quant;
magnetic resonance imaging
- MeSH:
Humans;
Intervertebral Disc Degeneration/diagnostic imaging*;
Cervical Vertebrae/diagnostic imaging*;
Magnetic Resonance Imaging/methods*;
Male;
Female;
Middle Aged;
Adult;
Intervertebral Disc/diagnostic imaging*;
Lipids
- From:
Chinese Journal of Medical Instrumentation
2025;49(1):61-66
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the clinical value of MRI modified water-lipid separation technique (mDIXON-Quant) in terms of T2* values and fat fraction (FF) values for evaluating the degree of cervical intervertebral disc degeneration.
METHODS:A total of 118 patients who underwent routine MRI of the cervical vertebra and the mDIXON-Quant examination in Fuyang People's Hospital from March 2019 to January 2024 were collected. The T2* values of C2/3 to C6/7 intervertebral discs and FF values of the upper and lower vertebral bodies were measured. Cervical intervertebral disc degeneration was graded according to the Pfirrmann criteria. The T2* values and FF values of different patients were compared with the Pfirrmann grades, and the correlation between T2* values, FF values, and Pfirrmann grades was analyzed by Spearman correlation.
RESULTS:The T2* values of cervical intervertebral discs in grades I, II, III, IV, and V all showed a decreasing trend ( P＜0.05). The decreasing order of FF values in the upper cervical vertebra was IV, V, III, II, and I ( F=93.28, P＜0.05), and the decreasing order of FF values in the lower cervical vertebra was IV, III, V, II, and I ( F=112.037, P＜0.05). Spearman correlation analysis showed that the T2* values of cervical intervertebral discs were negatively correlated with the Pfirrmann grades ( P＜0.05), and the FF values of the upper and lower vertebrae were positively correlated with the Pfirrmann grades ( P＜0.05).
CONCLUSION:The mDIXON-Quant technique can be used to quantify the T2* values and FF values of cervical intervertebral disc degeneration and plays an important role in accurate clinical diagnosis and evaluation of treatment effects.
