Effects of overweight and obesity on symptoms,overall condition and quality of life in patients with fibromyalgia syndrome
10.19723/j.issn.1671-167X.2024.06.009
- VernacularTitle:超重和肥胖对纤维肌痛综合征患者症状、整体病情及生活质量的影响
- Author:
Meijuan LONG
1
;
Yidan WANG
1
;
Shiya WU
1
;
Zihao LI
1
;
Yanting LI
1
;
Yang LI
1
;
Juan JIAO
1
Author Information
1. 中国中医科学院广安门医院风湿病科,北京 100053
- Publication Type:Journal Article
- Keywords:
Fibromyalgia syndrome;
Chronic pain;
Weight;
Weight loss
- From:
Journal of Peking University(Health Sciences)
2024;56(6):1001-1008
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of overweight and obesity(overweight/obesity)on symp-tom severity and quality of life in Chinese patients with fibromyalgia syndrome(FMS).Methods:A cross-sectional survey was used to collect general data on height,weight,gender and age of 435 FMS pa-tients who visited the rheumatology clinic of Guang'anmen Hospital from October 2018 to December 2021.The numbers of tender points,widespread pain index and symptom severity scale were used as diagnostic indicators of the disease.The pain visual analogue scale,Beck depression inventory,perceived stress scale(PSS),Pittsburgh sleep quality index(PSQI)and multidimensional fatigue scale were used to as-sess the severity of pain and negative emotions,stress perception,sleep quality,and fatigue symptoms of this disease.The revised fibromyalgia impact questionnaire,fibromyalgia symptom scale(FS)and quali-ty of life assessment scale(36 item short-form health survey,SF-36)were used to evaluate the overall condition and quality of life of the FMS patients.At the same time,50 healthy volunteers matched in gender and age were recruited as the control group.Covariance analysis was used to explore the effects of overweight/obesity on the FMS patients after adjusting for age and gender.Results:According to the Chinese body mass index(BMI)standard,there were 242(59％)and 170(41％)FMS patients in the normal weight group and overweight/obesity group,respectively,with average BMI of(21.66±1.42)kg/m2 and(26.25±1.83)kg/m2,respectively.Compared with the normal weight FMS patients,the overweight/obesity patients had higher PSS scores(P=0.010),PSQI sub-dimension sleep efficiency scores(P＜0.001)and FS scores(P=0.025),and lower SF-36 sub-dimension physical functioning scores(P=0.041).However,there were no statistical differences in the above indicators between nor-mal weight and overweight/obesity patients in the healthy control group(P＞0.05).Conclusion:Com-pared with normal-weight FMS patients,overweight/obesity patients have higher levels of perceived stress,lower sleep efficiency,and more severe fibromyalgia symptoms,as well as a low quality of life characterized by decreased physiological function.It is important for overweight/obesity FMS patients to control BMI actively in order to improve sleep efficiency,psychological state,physical functioning,and the overall condition.
