Consensus of Chinese experts on gut microbiota and fecal microbiota transplantation in inflammatory bowel disease (2025 edition).
10.3760/cma.j.cn441530-20241224-00422
- Collective Name:Parenteral and Enteral Nutrition Branch of the Chinese Medical Association;Chinese Society for the Promotion of Human Health Science and Technology;Committee on Gut Microecology and Fecal Microbiota Transplantation, Shanghai Preventive Medicine Association
- Publication Type:Journal Article
- MeSH:
Humans;
Fecal Microbiota Transplantation;
Inflammatory Bowel Diseases/microbiology*;
Gastrointestinal Microbiome;
Consensus;
China
- From:
Chinese Journal of Gastrointestinal Surgery
2025;28(3):225-235
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, significant progress has been made in the clinical and basic research on fecal microbiota transplantation (FMT) for the treatment of inflammatory bowel disease (IBD). With the continuous application of new microbiota-based diagnostic and therapeutic concepts in clinical practice, it is imperative to standardize the diagnostic and therapeutic processes of FMT for IBD and provide consensus recommendations based on the latest evidence from evidence-based medicine for clinical practitioners. Organized by the Chinese Society for Parenteral and Enteral Nutrition of the Chinese Medical Association, the Gut Microbiota and FMT Committee of the Chinese Society for Human Health Sciences, and the Gut Microbiota Committee of the Shanghai Preventive Medicine Association, and with reference to the latest international consensus and relevant research advancements, this consensus integrates the clinical practice experience of domestic experts to establish the "Consensus of Chinese experts on gut microbiota and fecal microbiota transplantation in inflammatory bowel disease (2025 edition)". This consensus provides 29 recommendations focusing on the selection of FMT indications, gut microbiota analysis, donor selection and quality control for IBD transplantation, considerations during the transplantation period, selection of transplantation routes and dosages, management of FMT-related complications, and future research directions, aiming to offer standardized guidance for the clinical application of FMT in the treatment of IBD.
