Best evidence summary for the fertility management in testicular cancer patients.
- Author:
Cang-Mei FU
1
;
Ya HU
2
;
Ao-Xi LIANG
1
;
Xue FU
2
Author Information
1. Department of Oncology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China.
2. Department of Urology, The Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, China.
- Publication Type:Journal Article
- Keywords:
testicular cancer； fertility； evidence summary； evidence-based nursing
- MeSH:
Humans;
Male;
Evidence-Based Medicine;
Fertility;
Fertility Preservation;
Testicular Neoplasms/therapy*;
Systematic Reviews as Topic
- From:
National Journal of Andrology
2025;31(6):526-534
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To summarize the relevant evidence of testicular cancer patients' fertility management which provides a basis for fertility guidance for young testicular cancer patients.
METHODS:The evidence, guidelines, expert consensus, evidence summary, systematic review and Meta-analysis on fertility-related clinical decision-making were searched from computer decision support systems, relevant guideline websites, evidence-based databases, original research databases, and professional association websites at home and abroad. The search period was set dating from the establishment of the database to July 2024. Two researchers with evidence-based nursing research background independently completed the quality evaluation, evidence extraction and summary of the literature.
RESULTS:A total of 21 articles were selected, including 4 clinical decisions, 8 guidelines, 4 expert consensuses, 3 systematic reviews and 2 Meta-analyses. Thirty-three pieces of best evidence from six aspects were summarized, including fertility assessment, fertility counseling, fertility preservation timing, fertility preservation regimen, anti-tumor therapy and fertility, and contraceptive timing.
CONCLUSION:The best evidence summarized in this study provides a basis for clinical medical staff to carry out fertility management in testicular cancer patients. In clinical application, medical staff need to fully consider the patient's wishes in combination with the clinical situation, and promote the maximum benefit of the patient, so as to further improve the life quality of the patients.
