Irreversible electroporation for the treatment of prostate cancer: An update.
- Author:
Xiao-Xu JIN
1
;
Xiao-Dong ZHAO
2
;
Song XU
1
Author Information
1. Department of Urology, Jinling Hospital Affiliated to Nanjing University School of Medicine, Nanjing, Jiangsu 210002, China.
2. Department of Urology, General Hospital of Eastern Theater Command, Nanjing, Jiangsu 210002, China.
- Publication Type:English Abstract
- Keywords:
prostate cancer;
irreversible electroporation;
nanoknife;
focal therapy
- MeSH:
Humans;
Male;
Prostatic Neoplasms/therapy*;
Electroporation/methods*
- From:
National Journal of Andrology
2025;31(1):76-80
- CountryChina
- Language:Chinese
-
Abstract:
Prostate cancer (PCa) is globally the most prevalent malignancy in the male genitourinary system, with a continuously ascending incidence in China. For the treatment of localized PCa, radical prostatectomy and radiotherapy have demonstrated effective suppression of the tumor, but with obvious complications that markedly compromise the life quality of the patients. Focal therapy, by targeting the principal tumor foci, can largely reduce the incidence of complications. In this context, irreversible electroporation represents an emerging modality of focal treatment capable of ablating the tumor as thoroughly as possible while sparing such critical structures as the urethra, rectum and neurovascular bundles from thermal damage, and thus offers a promising option for the management of localized PCa. This article presents an overview of the latest advances in the studies of irreversible electroporation.
