Male genital system lymphoma:Clinicopathological analysis of 80 cases
10.13263/j.cnki.nja.2025.02.006
- VernacularTitle:男性生殖系统淋巴瘤80例临床病理分析
- Author:
Xiao-die ZHOU
1
;
Rong-xin QI
;
Bo YU
;
Xuan WANG
;
Qun-li SHI
;
Qiu RAO
;
Wei BAO
Author Information
1. 东部战区总医院,病理科,江苏南京 210002
- Publication Type:Journal Article
- Keywords:
male reproductive system;
lymphoma;
clinicopathology;
prognosis
- From:
National Journal of Andrology
2025;31(2):138-143
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinicopathological features and differential diagnosis of male genital system lympho-ma(MGSL).Methods:We retrospectively analyzed the clinicopathological and immunophenotypic features and prognosis of 80 ca-ses of MGSL.Results:The onset age of the MGSL patients ranged from 4 to 85(median 62)years old.All the cases showed non-specificity of the imaging features and clinical manifestations.MGSL was located mainly in the testis(n=66),followed by the pros-tate(n=7),epididymis(n=3),scrotum(n=3)and penile glans(n=1).Diffused large B cell lymphoma(DLBCL)was the most common pathological type(n=62),next came extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue(MALT)(n=7)and other rare types(n=12).During the 1-112-month follow-up of 10 of the 19 patients,1 died at 1 month af-ter diagnosed with prostatic B-lymphoblastic lymphoma(B-LBL)and another 1 died at 50 months after diagnosed with testicular DLBCL.Conclusion:MGSL is rare clinically,mainly of the DLBCL type pathologically,lacking specificity in clinical symptoms and imaging manifestation.The definite diagnosis of the malignancy depends on histopathology combined with related molecular exami-nation and immunohistochemical labeling,and R-CHOP chemotherapy is the first choice for its treatment.
