Recent Advances in Peripheral Immunoscore in Lung Cancer.
10.3779/j.issn.1009-3419.2025.102.21
- Author:
Fan XU
1
;
Bin LUO
1
;
Jianhui TIAN
1
;
Yun YANG
1
;
Zhenyang CHENG
1
;
Youjun LIU
1
Author Information
1. Department of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine,
Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China.
- Publication Type:English Abstract
- Keywords:
Immunotherapy;
Lung neoplasms;
Peripheral immunoscore;
Predictive models
- MeSH:
Humans;
Lung Neoplasms/drug therapy*;
Tumor Microenvironment;
Prognosis
- From:
Chinese Journal of Lung Cancer
2025;28(5):379-384
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer is the malignant tumor with the highest morbidity and mortality. The tumor-node-metastasis (TNM) staging has gradually shown its limitations in the accurate prediction of lung cancer, so it is urgent to construct a new clinical predictive model to guide the prevention and treatment of lung cancer. In recent years, as a comprehensive evaluation system based on peripheral immune related parameters, the value of peripheral immunoscore in the construction of predictive model has gradually become prominent. By quantifying the quantity and proportion of immune components in peripheral blood, the score can dynamically reflect the overall immune function and tumor microenvironment characteristics of the body. This paper systematically summarizes the latest research progress of peripheral immunoscore in early diagnosis, drug efficacy prediction, early warning of adverse reactions and prognosis evaluation of lung cancer, aiming to tap its potential clinical application value and provide some ideas and directions for developing new lung cancer-related predictive models.
.
