Research Progress on the Relationship between Intratumor Microbiota and Lung Cancer.
10.3779/j.issn.1009-3419.2025.101.05
- Author:
Yangtong ZHU
1
;
Jiawei CHEN
1
;
Yanqian ZHU
1
;
Linyu WU
1
Author Information
1. The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine),
First Clinical School of Medicine, Zhejiang Chinese Medical University, Hangzhou 310006, China.
- Publication Type:English Abstract
- Keywords:
Biomarker;
Intratumor microbiota;
Lung neoplasms;
Mechanism of action
- MeSH:
Humans;
Lung Neoplasms/diagnosis*;
Microbiota;
Animals;
Prognosis
- From:
Chinese Journal of Lung Cancer
2025;28(4):304-308
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer has the highest incidence and mortality of any cancer in the world. In recent years, with the development of microbial detection technology, the intratumor microbiota has gradually become a hot spot and frontier in the field of lung cancer research. Studies have found that the microbiota present in tumors can influence the development of lung cancer in a variety of ways. In addition, the intratumor microbiota can be used as a potential biomarker for the diagnosis and prognosis assessment of lung cancer, and the regulation of the intratumor microbiota of lung cancer is expected to become a new type of lung cancer treatment. In this paper, we reviewed the latest research progress on the relationship between intratumor microbiota and lung cancer, summarized the origin and characteristics of intratumor microbiota, discussed the mechanism of its influence on the occurrence and development of lung cancer, and explored its potential applications in the diagnosis, treatment and prognosis of lung cancer.
.
