Application of Nano-drug Delivery Technology in Overcoming Drug Resistance
in Lung Cancer.
10.3779/j.issn.1009-3419.2024.101.30
- Author:
Yingchun LU
1
;
Chunyu WANG
2
;
Bin LIU
3
Author Information
1. School of Medicine, University of Electronic Science and Technology of China, Chengdu 610054, China.
2. School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 610032, China.
3. Department of Medical Oncology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital
of University of Electronic Science and Technology of China, Chengdu 610042, China.
- Publication Type:English Abstract
- Keywords:
Drug resistance;
Lung neoplasms;
Nano-drug delivery technology
- MeSH:
Humans;
Lung Neoplasms/diagnosis*;
Drug Resistance, Neoplasm/drug effects*;
Drug Delivery Systems/methods*;
Antineoplastic Agents/pharmacology*;
Animals;
Nanoparticles/chemistry*;
Nanotechnology/methods*
- From:
Chinese Journal of Lung Cancer
2024;27(11):864-872
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer is one of the most malignant tumor, representing a significant threat to human health. In China, its mortality rate is the highest among all malignant tumors. The occurrence of drug resistance has resulted in unfavourable prognosis for patients with lung cancer, and overcoming drug resistance is a significant challenge that needs to be addressed. Nano-drug delivery technology has been an important approach to overcome drug resistance in lung cancer. Targeting to the mechanisms of drug resistance, by enabling the combined delivery of drugs, increasing the efficiency of drug delivery and improving the targeting and safety of drugs, nano-drug delivery technology offers a novel approach to tackling drug resistance in lung cancer. This paper describes the current status of lung cancer treatment, mechanisms of drug resistance, strategies to overcome drug resistance, and the application of nanotechnology in the diagnosis and treatment of lung cancer. In addition, it summarizes the recent research progress on the application of nano-drug delivery technology to overcome drug resistance in lung cancer. Finally, the current prospects and challenges of nano-drug delivery technology are discussed.
.
