Research Progress of Flow Cytometry in Diagnosis and Treatment of Myelodysplastic Syndrome——Review
10.19746/j.cnki.issn1009-2137.2025.04.044
- VernacularTitle:流式细胞术在MDS诊治应用中的研究进展
- Author:
Qiu-Cheng ZHANG
1
;
Bao-An CHEN
1
;
Jian CHENG
1
Author Information
1. 东南大学医学院,东南大学附属中大医院血液科,江苏南京 210009
- Publication Type:Journal Article
- Keywords:
myelodysplastic syndrome;
flow cytometry;
immunophenotype detection;
diagnosis;
prognosis;
efficacy assessment
- From:
Journal of Experimental Hematology
2025;33(4):1222-1227
- CountryChina
- Language:Chinese
-
Abstract:
Flow cytometry(FCM),as an important method for the diagnosis of acute myeloid leukemia(AML),has been widely used in myelodysplastic syndrome(MDS)in recent years.FCM can effectively identify and characterize abnormal hematopoietic cells through immunophenotyping,particularly in the diagnosis of MDS with insignificant morphological abnormalities.Additionally,FCM can monitor disease progression and minimal residual disease(MRD)by detecting phenotypic changes and evaluate treatment efficacy.This article reviews the latest research progress of FCM in the immunophenotyping,prognosis and efficacy evaluation of MDS.
