Medium- and long-term efficacy of percutaneous mechanical thrombectomy with stent implantation in patients with iliac vein stenosis and thrombosis.
10.3724/zdxbyxb-2024-0537
- Author:
Chunlun CHEN
1
;
Chenyang QIU
2
;
Lan SHEN
3
;
Renda ZHU
4
;
Huaji ZHOU
5
;
Hongkun ZHANG
6
Author Information
1. Department of Vascular Surgery, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. 185198381@qq.com.
2. Department of Vascular Surgery, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
3. Department of Vascular Surgery, the First Hospital of Jiaxing Affiliated to Jiaxing University, Jiaxing 314001, Zhejiang Province, China.
4. Department of Vascular Surgery, Haining People's Hospital, Jiaxing 314400, Zhejiang Province, China.
5. Department of Vascular Surgery, the No.1 People's Hospital of Pinghu, Jiaxing 314200, Zhejiang Province, China.
6. Department of Vascular Surgery, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. 1198050@zju.edu.cn.
- Publication Type:Journal Article
- Keywords:
Efficacy;
Iliac vein compression syndrome;
Lower extremity deep venous thrombosis;
Percutaneous mechanical thrombectomy;
Post-thrombotic syndrome;
Stent implantation
- MeSH:
Humans;
Stents;
Iliac Vein/pathology*;
Venous Thrombosis/surgery*;
Thrombectomy/methods*;
Female;
Male;
Middle Aged;
Aged;
Adult;
Constriction, Pathologic/surgery*;
Treatment Outcome;
Follow-Up Studies
- From:
Journal of Zhejiang University. Medical sciences
2025;54(1):108-114
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVES:To investigate the medium- and long-term efficacy of percutaneous mechanical thrombectomy (PMT) combined with stent implantation for treatment of iliac vein stenosis with lower extremity deep venous thrombosis (LEDVT).
METHODS:Clinical and follow-up data of 125 patients with iliac vein stenosis and LEDVT who underwent PMT and stent implantation at five hospitals in northern Zhejiang province from January 2017 to June 2021 were collected. The thrombus clearance rate, thrombus recurrence rate, patency rate of iliac vein stents and post-thrombotic syndrome (PTS) occurrence rate were documented, and safety indicators such as bleeding, death, pulmonary embolism, stent fracture and displacement were assessed.
RESULTS:Among 125 patients, for clearance of limb thrombosis, there were 8 cases of grade I (6.4%), 10 cases of grade II (8.0%), and 107 cases of grade III (85.6%). Patients were followed up for a median period of 74 months. According to the Villalta score, the recurrence rates of limb thrombosis at 12, 24 and 36 months were 8.48%, 8.93% and 10.91%; the iliac vein patency rates were 91.52%, 91.07%, and 89.09%; and the incidences of PTS were 5.08%, 5.36% and 6.36%, respectively. There were no major adverse events such as death, massive pulmonary embolism or severe hepatic and renal insufficiency, and no readmission intervention events due to stent fracture or other incidence were found.
CONCLUSIONS:PMT combined with iliac vein stent implantation is effective for patients with iliac vein stenosis complicated by LEDVT with good medium- and long-term efficacy and safety, which is worthy of clinical application.
