Research progress and optimization strategies for early screening of type 1 diabetes.
10.7499/j.issn.1008-8830.2505123
- Author:
Qi-Jun SONG
1
;
Yan SUN
1
Author Information
1. Department of Pediatric Endocrinology, Shandong Provincial Hospital Affliated to Shandong First Medical University, Jinan 250021, China.
- Publication Type:English Abstract
- Keywords:
Diabetes-related antibody;
Disease mechanism;
Early screening;
Type 1 diabetes
- MeSH:
Diabetes Mellitus, Type 1/diagnosis*;
Humans;
Early Diagnosis;
Autoantibodies/blood*;
Mass Screening/methods*
- From:
Chinese Journal of Contemporary Pediatrics
2025;27(11):1310-1316
- CountryChina
- Language:Chinese
-
Abstract:
The prevalence of type 1 diabetes (T1DM) is increasing annually, and its complications seriously impair the quality of life of affected children. Early screening for T1DM helps reduce the occurrence of diabetic ketoacidosis, protect β-cell function, and delay disease onset in high-risk populations. This article summarizes current domestic and international screening technologies for T1DM. Screening methods remain centered on detection of diabetes-related antibodies and glycometabolic markers, while factors related to disease pathogenesis hold promise as sensitive screening markers. Expanding T1DM screening in China is expected to improve early diagnosis and treatment.
