Granuloma faciale and Takayasu arteritis in a child: a case report.
10.7499/j.issn.1008-8830.2504185
- Author:
Wei LIAO
1
;
Juan LONG
1
;
Jian-Ping TANG
1
;
Dan-Ni WO
;
Ye SHU
1
;
Zhu WEI
1
Author Information
1. Department of Dermatology, Affiliated Children's Hospital of Xiangya School of Medicine, Central South University/Hunan Children's Hospital, Changsha 410007, China.
- Publication Type:English Abstract
- Keywords:
Child;
Granuloma faciale;
Takayasu arteritis
- MeSH:
Humans;
Male;
Child;
Takayasu Arteritis/diagnosis*;
Facial Dermatoses/diagnosis*
- From:
Chinese Journal of Contemporary Pediatrics
2025;27(10):1266-1270
- CountryChina
- Language:Chinese
-
Abstract:
An 11-year-old boy presented with erythematous plaques over the bilateral mandibular and mental regions for 2 years, accompanied by cough and dyspnea for more than 2 months. Chest computed tomography angiography revealed marked stenosis of the right pulmonary artery, irregular aortic caliber, and aortic wall thickening. Histopathological examination of the skin lesion, including immunohistochemistry and special stains, confirmed a chronic suppurative inflammation. Whole-exome sequencing was negative. A final diagnosis of granuloma faciale and Takayasu arteritis was established. Combination therapy with systemic tocilizumab, prednisone, and methotrexate, along with topical 0.1% tacrolimus ointment, resulted in a favorable clinical response. This report summarizes the clinical features of a pediatric case of granuloma faciale and Takayasu arteritis and reviews the etiology, diagnostic approach, and current treatment strategies for the disorders, aiming to enhance clinicians' understanding of these conditions.
