Risk factors for recurrent plastic bronchitis in children with Mycoplasma pneumoniae pneumonia.
10.7499/j.issn.1008-8830.2503149
- Author:
Wan-Yi LI
1
;
Shu-Ying WANG
1
;
Hai-Zhen WANG
1
;
Qi-Jun ZHAO
1
;
Tao ZHANG
1
;
Wen-Yuan WANG
1
;
Yuan HUO
1
;
Yong-Jun WANG
1
Author Information
1. Second Department of Pediatric Respiratory Medicine, Gansu Province Maternity and Child Health Hospital/Gansu Province Central Hospital, Lanzhou 733050, China.
- Publication Type:Journal Article
- Keywords:
Child;
Mycoplasma pneumoniae pneumonia;
Plastic bronchitis;
Recurrence;
Risk factor
- MeSH:
Humans;
Pneumonia, Mycoplasma/complications*;
Male;
Female;
Risk Factors;
Recurrence;
Child, Preschool;
Bronchitis/etiology*;
Child;
Retrospective Studies;
Logistic Models;
Infant;
ROC Curve;
Adolescent
- From:
Chinese Journal of Contemporary Pediatrics
2025;27(10):1220-1226
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVES:To identify risk factors for recurrent plastic bronchitis (PB) among children with Mycoplasma pneumoniae pneumonia (MPP).
METHODS:The clinical data of children with MPP complicated by PB who underwent bronchoscopy at Gansu Province Maternity and Child Health Hospital between July 2023 and January 2025 were retrospectively analyzed. Patients were grouped into a single-episode PB group and a recurrent PB group according to the number of PB episodes. Multivariable logistic regression was used to identify risk factors for recurrent PB. Receiver operating characteristic (ROC) curve analysis was used to assess the diagnostic performance of individual and combined predictors.
RESULTS:A total of 264 children were included; 188 (71.2%) had a single episode of PB and 76 (28.8%) had recurrent PB. Multivariable logistic regression analysis showed that decreased serum albumin, atelectasis, and fever persisting beyond 72 hours after the initial bronchoscopy were significantly associated with recurrent PB (all P<0.05). The combination of these predictors yielded a sensitivity of 82.9%, specificity of 61.7%, and an area under the ROC curve of 0.777 (95%CI: 0.714-0.839), outperforming any single predictor (P<0.05).
CONCLUSIONS:In children with MPP complicated by PB, decreased serum albumin, the presence of atelectasis, and fever persisting beyond 72 hours after the initial bronchoscopy are associated with an increased risk of PB recurrence. In such cases, early repeat or multiple bronchoscopic interventions should be considered.
