Colonoscopy in infants: procedure and disease spectrum analysis of 184 cases.
10.7499/j.issn.1008-8830.2502085
- Author:
Xiao-Li FU
1
;
Xu-Xia WEI
1
;
Jun-Jie XU
1
;
Ning XUE
1
;
Hong-Ling CHEN
1
;
Le ZHANG
1
Author Information
1. Department of Gastroenterology, Children's Hospital Affiliated to Shandong University/Jinan Children's Hospital, Jinan 250022, China.
- Publication Type:Journal Article
- Keywords:
Colonoscopy;
Disease spectrum;
Infant;
Infantile-onset inflammatory bowel disease;
Polyp
- MeSH:
Humans;
Infant;
Colonoscopy;
Male;
Female;
Retrospective Studies;
Infant, Newborn;
Diarrhea/etiology*;
Gastrointestinal Hemorrhage/etiology*
- From:
Chinese Journal of Contemporary Pediatrics
2025;27(8):917-922
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVES:To investigate the underlying causes and clinical manifestations in infants undergoing colonoscopy, and to analyze changes in disease spectrum.
METHODS:Clinical data from 180 infants who underwent a total of 184 colonoscopies at the Department of Gastroenterology, Children's Hospital Affiliated to Shandong University from January 2015 to December 2024 were retrospectively analyzed. Patients were grouped by age: ≤6 months (n=41) and >6-12 months (n=139); and by examination period: 2015-2019 (n=83) and 2020-2024 (n=97). Primary causes for performing colonoscopy, final diagnoses, and disease spectrum evolution were assessed.
RESULTS:Among 184 colonoscopies, the leading causes prompting examination were hematochezia (37.8%, 68/180), diarrhea (36.7%, 66/180), and co-occurring hematochezia and diarrhea (21.1%, 38/180). Causes for performing colonoscopy differed significantly by age group (P<0.05). Colonic polyps were only detected in the >6-12 months group (P<0.05). Compared to the 2015-2019 group, the 2020-2024 group had fewer food allergy-related gastrointestinal diseases (P<0.05) but more colitis (P<0.05).
CONCLUSIONS:Colonoscopy is essential for diagnosing infantile digestive disorders, with disease spectra varying by age and time period.
