Research progress on the relationship between gut microbiota and childhood bronchial asthma.
10.7499/j.issn.1008-8830.2411113
- Author:
Lei YU
1
;
Mao-Lan WU
1
;
Xiang-Rong ZHENG
1
Author Information
1. Children's Medical Center, Xiangya Hospital of Central South University, Changsha 410008, China.
- Publication Type:English Abstract
- Keywords:
Bronchial asthma;
Child;
Gut microbiota;
Pathogenesis;
Treatment
- MeSH:
Humans;
Asthma/etiology*;
Gastrointestinal Microbiome/physiology*;
Child
- From:
Chinese Journal of Contemporary Pediatrics
2025;27(5):623-628
- CountryChina
- Language:Chinese
-
Abstract:
Bronchial asthma (asthma) is a complex inflammatory airway disease affecting approximately 100 million children worldwide, imposing a heavy burden on society and families. Studies have shown that the gut microbiota plays a significant role in the occurrence and development of childhood asthma. This paper reviews the research progress on the relationship between gut microbiota and childhood asthma. By elucidating the composition, function, and relationship with the host of gut microbiota, the impact of changes in its composition and function on the development of asthma is revealed. Furthermore, the potential value and application prospects of modulating gut microbiota as a new strategy for asthma treatment are discussed, providing a theoretical reference for in-depth research on the relationship between gut microbiota and the onset of childhood asthma and the development of new therapeutic approaches.
