Guideline for transfusion management in Chinese children with transfusion-dependent thalassemia (2025).
10.7499/j.issn.1008-8830.2410119
- Collective Name:Committee of Thalassemia Prevention and Treatment, China Maternal and Child Health Association;Subspecialty Group of Hematology, Society of Pediatrics, Chinese Medical Association;China Thalasemia Prevention and ControlCollaboration Network;Editorial Board of Chinese Journal of Contemporary Pediatrics
- Publication Type:English Abstract
- Keywords:
Blood transfusion;
Child;
Guideline;
Management;
Transfusion-dependent thalassemia
- MeSH:
Humans;
Thalassemia/therapy*;
Blood Transfusion/standards*;
Child;
East Asian People
- From:
Chinese Journal of Contemporary Pediatrics
2025;27(5):505-514
- CountryChina
- Language:Chinese
-
Abstract:
Thalassemia is a group of hereditary disorders characterized by ineffective erythropoiesis due to hemoglobin synthesis abnormalities, resulting in varying degrees of chronic anemia. Patients with transfusion-dependent thalassemia rely on lifelong regular blood transfusions and iron chelation therapy. Proper transfusion treatment and management of transfusion-related complications are essential to ensure the growth and development of pediatric patients and to improve their quality of life. The guideline working group has developed the guideline by referencing domestic and international guidelines, expert consensus, and relevant studies. The aim is to further standardize the transfusion management of transfusion-dependent thalassemia in children in China.
