Guidelines for iron chelation therapy in thalassemia in China (2025).
10.7499/j.issn.1008-8830.2411001
- Collective Name:Committee of Thalassemia Prevention and Treatment, China Maternal and Child Health Association;Subspecialty Group of Hematology, Society of Pediatrics, Chinese Medical Association;China Thalassemia Prevention and Control Collaboration Network;Editorial Board of Chinese Journal of Contemporary Pediatrics
- Publication Type:English Abstract
- Keywords:
Guideline;
Iron chelation therapy;
Iron overload;
Thalassemia
- MeSH:
Humans;
Thalassemia/drug therapy*;
Iron Chelating Agents/therapeutic use*;
Iron Overload/diagnosis*;
Chelation Therapy
- From:
Chinese Journal of Contemporary Pediatrics
2025;27(4):377-388
- CountryChina
- Language:Chinese
-
Abstract:
Iron overload is a major complication of thalassemia, clinically manifested as heart failure, liver cirrhosis, diabetes, growth and development retardation, and delayed sexual development, with severe cases leading to death. Standardized iron chelation therapy is essential to ensure long-term and high-quality survival for patients. This guideline provides recommendations on methods for detecting iron overload, the timing for initiating iron chelation therapy, treatment strategies for transfusion-dependent and non-transfusion-dependent thalassemia, and special circumstances regarding iron chelation therapy, serving as a reference for iron chelation treatment in thalassemia.
