Application and considerations of recombinant human growth hormone in treating growth disorders in children with chronic kidney disease.
10.7499/j.issn.1008-8830.2410023
- Author:
Jian-Hua ZHOU
1
Author Information
1. Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 China.
- Publication Type:English Abstract
- Keywords:
Child;
Chronic kidney disease;
Growth disorder;
Recombinant human growth hormone
- MeSH:
Humans;
Human Growth Hormone/adverse effects*;
Child;
Recombinant Proteins/adverse effects*;
Renal Insufficiency, Chronic/complications*;
Growth Disorders/etiology*
- From:
Chinese Journal of Contemporary Pediatrics
2025;27(2):133-138
- CountryChina
- Language:Chinese
-
Abstract:
Growth disorders are one of the common complications of chronic kidney disease (CKD) in children, adversely affecting both the quality of life and survival time of CKD patients. Recombinant human growth hormone (rhGH) is an effective treatment for growth disorders in children with CKD. This article reviews the mechanisms underlying growth disorders in children with CKD, the therapeutic effects, safety, and precautions of rhGH, and long-term management of diagnosis and treatment of this disorder.
